Medical English | Day22
2014/11/30 医学生

    

    

     hypoxia

     [ha?'p?ks?]

     n. [医] 低氧；组织缺氧；氧不足

     词根hypo-表示少，不足

     hyposecretion分泌不足

     hypoalimentation 营养不良；滋养不足

     词组hypoxic hypoxia乏氧性缺氧

     respiratory hypoxia呼吸性缺氧

     hypobaric hypoxia低压缺氧；急性低氧

     Fetal hypoxia胎儿缺氧

     ischemic hypoxia缺血性缺氧

     cytopathic hypoxia细胞病性缺氧；细胞病理性缺氧

     例句The researchers noted that cognitive issues identified during the prospective study appear to be associated with hypoxia rather than with the quality and duration of sleep.

     研究人员指出，在前瞻性研究中被证明认知障碍的发生似乎是与缺氧有关，而与睡眠质量和时间无关。

     article.yeeyan.org

     Question肖锋 翻译和整理

     What is dialysis disequilibrium syndrome? When is it most likely to occur?

     什么是透析失衡综合征？它最有可能在什么时间发生？

     AnswerDialysis disequilibrium syndrome refers to acute neurologic dysfunction attributed to dialysis treatment-related cerebral edema. It is more likely to occur during or immediately after the first hemodialysis session.

     透析失衡综合征是指与透析治疗相关的脑水肿所致的急性神经功能紊乱。它通常发生在第一次血液透析过程中或结束后(Am J EM, epub, 9/26/14)。

     Life Outcomes of Anterior Temporal Lobectomy: Serial Long-term Follow-up Evaluations.

     颞叶前部切除术后生存结局：连续长期随访研究

     Jana E Jones ,Jacquelyn B Blocher ,Daren C Jackson

     Neurosurgery

     2013-09-19

     索引：Neurosurgery.2013 Sep 19;

     中文摘要来源：尹华翻译 董润审核

     BACKGROUND:

     At three time points, this study examined long-term psychosocial life outcomes of individuals who underwent anterior temporal lobectomy (ATL) compared to individuals with temporal lobe epilepsy (TLE) that were medically managed.

     OBJECTIVE:

     To examine seizure frequency, employment, driving, independent living, financial independence, mental health, and quality of life at each follow-up assessment, as well as predictors of outcomes.

     METHODS:

     All participants were diagnosed with medically intractable complex partial seizures of temporal lobe origin with or without secondary generalization. A structured clinical interview was utilized at all three time points. Information was obtained regarding seizure frequency, anti-epilepsy medications, employment, driving status, financial assistance, and independent living. Additionally, questions regarding quality of life, satisfaction with surgery, and presence of depression or anxiety were included. Participants were, on average, 17 years post-surgery.

     RESULTS:

     Surgery resulted in significantly improved and sustained seizure outcomes. At the first, second, and third follow-ups, 67%, 72%, and 67% of participants in the surgery group remained seizure-free in the year prior to follow-up interview. At each follow-up, 97%, 84%, and 84% reported that they would undergo surgery again. Seizure freedom predicted driving outcomes at all three time points, but was not a significant predictor for employment, independent living, or financial independence. Psychosocial life outcomes in the surgical group were improved and maintained over time when compared to the medically managed group.

     CONCLUSION:

     This systematic long-term investigation provides strong support for the positive impact of ATL on psychosocial life outcomes including driving, employment, independent living, and financial independence.

     背景

     本研究在3个时间点上研究了颞叶前部切除术后的社会心理结局，并与接受药物治疗的颞叶癫痫患者进行了对比。

     目的

     我们在每个随访阶段研究了癫痫发作频率、职业状况、驾驶状况、独立生活能力、经济独立情况、心理健康状况以及生活质量，并探索了结局的预测因素。

     方法

     所有研究对象均诊断了起源于颞叶的药物难治性复杂部分性癫痫，继发或不继发全面性发作，我们在3个时间点均进行了规范的临床访视，获取的信息包括癫痫发作频率、抗癫痫药物的使用、职业状况、驾驶状况、经济情况以及独立生活能力。我们还询问了术后生活质量、手术的满意度以及是否出现抑郁或焦虑等精神症状。研究对象在平均17年前接受了手术。

     结果

     颞叶前部切除术显著改善并维持了癫痫的结局。在三次随访中，分别有67%，72%，67%的患者在随访前一年未发作癫痫。同时，分别有97%，84%，84%的患者表示，如果重新选择，仍会选择手术治疗。三次随访结果均显示，癫痫的控制是驾驶情况的预测因素，但并非职业、独立生活能力或经济独立的预测因素。手术组患者在社会心理方面的改善较药物治疗组更显著，而且得到了维持。

     结论

     本项长期系统性研究表明，颞叶前部切除术可改善癫痫患者的社会心理结局，包括驾驶、职业、独立生活能力及经济独立。

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